Easy way to buy generic medicine?
Generic medicine contain the same active ingredients, in the very same strength, as brand-name drugs. When a medicine is first developed, the pharmaceutical company that discovers and markets it receives a patent on its new drug. The patent usually lasts for 20 years, to give the originating company a chance to recoup its research investment. After the patent expires, a generic version of the drug may become available.
Are generic drugs as good as brand-names?
Generic pharmaceutical manufacturers must prove to the FDA that their version of a drug:
It contains the same active ingredient;
is identical in strength,
dosage form, and route of administration;
has the same indications, dosing, and labeling;
provides the same efficacy and safety profile to patients.
Regulation:
Most nations require generic drug manufacturers to prove that their formulations are bioequivalent to their brand-name counterparts.Bioequivalence does not mean generic drugs must be exactly the same as the brand-name product ("pharmaceutical equivalent"). Chemical differences may exist; a different salt or ester may be used, for instance. Different inactive ingredients means that the generic may look different from the originator brand. However, the therapeutic effect of the drug must be the same. Most small molecule drugs are accepted as bioequivalent if their pharmacokinetic parameters of area under the curve (AUC) and maximum concentration (Cmax) are within a 90% confidence interval of 80–125%; most approved generics are well within this limit.
Comments
Post a Comment